Antagonism of neuromuscular block by physostigmine in man.
نویسنده
چکیده
In 20 adult patients undergoing inguinal herniorrhaphy neuromuscular block was induced with tubocurarine 10 mg. In 10 patients, neostigmine 1--2 mg antagonized the block and restored the twitch response to its baseline value. Physostigmine, up to 4 mg, did not produce significant antagonism of the neuromuscular block.
منابع مشابه
Antagonists to neuromuscular blocking agents. An experimental study.
T h : antagonism between tubocurarine and alcuronium chloride on the one hand and neostigmine, physostigmine, edrophonium and ambenonium on the other have been investigated. A quantitative measure of antagonism was obtained on the rat diaphragm preparation and it was found that in general the antagonists were more effective against alcuronium chloride than against tubocurarine. The antagonist d...
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ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 50 10 شماره
صفحات -
تاریخ انتشار 1978